In-cell chemical network driven by neo-PTMs

Research

Publications

In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin

Research
Outline

Our research aims are 1) develop chemical methods to introducing artificial or hitherto unknown post-translational modifications (neo-PTMs) into proteins, 2) detect change of endogenous chemical network driven by the neo-PTMs, and 3) understand their biological outputs.
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A01
Chemical catalysts
Project leader/Dr. Kenzo Yamatsugu
A02
Synergistic effects
Principal Investigator/Dr. Yoshihiro Sohtome
A03
Biological outcomes
Principal Investigator/Dr. Tadahiro Shimazu