In-cell chemical network driven by neo-PTMs
Research
Publications
Catalytic oxidative carbon–carbon bond-formations of benzene-1,2-diols
Research
Outline
Outline
Our research aims are 1) develop chemical methods to introducing artificial or hitherto unknown post-translational modifications (neo-PTMs) into proteins, 2) detect change of endogenous chemical network driven by the neo-PTMs, and 3) understand their biological outputs.
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About
A01
Chemical catalysts
Project leader／Dr. Kenzo Yamatsugu
A02
Synergistic effects
Principal Investigator／Dr. Yoshihiro Sohtome
A03
Biological outcomes
Principal Investigator／Dr. Tadahiro Shimazu
Publication
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Publications
Catalytic oxidative carbon–carbon bond-formations of benzene-1,2-diols
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Publications
A chemical catalyst enabling histone acylation with endogenous acyl-CoA
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Presentations
Dr. Yamatsugu gave an invited lecture in The 82nd Annual Meeting of The Japan Cancer Association.
News
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News
neo-PTMs workshop was held at the 23rd Annual Meeting of the Protein Science Society of Japan (July 6, 2023, Nagoya).
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News
The 2nd Administrative Group Meeting was held at Chiba University.
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News
neo-PTMs symposium will be held at the 96th Annual Meeting of the Japanese Biochemical Society (November 1, 2023, Fukuoka).